I have used Accordance for research in the Dead Sea Scrolls, Aramaic Targums, the Mishnah, the Pseudepigrapha, Josephus, the Septuagint, the Apostolic Fathers, Ireneaus, and Justin Martyr. The Dead Sea Scrolls, Aramaic Targums, and the Mishnah tagged texts saved me countless hours of time I would have otherwise spent on painstakingly looking up the words in a Hebrew/Aramaic Lexicon. In addition, because most of this literature is unpointed, I have been able to work with it much more easily thanks to Accordance. Recently, my research has shifted into early Christian literature and I have used the tagged Greek texts of the AF, Ireneaus and Justin to great effect. While I infrequently conduct detailed grammatical research, Accordance provides the most user-friendly and intuitive search engines out there.
Without getting into a detailed discussion of using Accordance for research, I’ll be content to mention one very convenient feature. If you are working with a Greek text (or Hebrew or Aramaic for that matter) and you want to research a word in the various tools that you have (including Lexicons, Grammars, Commentaries, Bible Notes, etc.) you simply right click the mouse and select “Search All Tools”. A list of all the occurrences of that word in all your tools is generated. You simply select which the tool you want to look at and a new window appears with that tool.